By Sam Kean
From New York occasions bestselling writer Sam Kean comes extra exceptional tales of technological know-how, historical past, language, and song, as informed by way of our personal DNA.
In The Disappearing Spoon, bestselling writer Sam Kean unlocked the mysteries of the periodic desk. within the VIOLINIST'S THUMB, he explores the wonders of the paranormal development block of lifestyles: DNA.
There are genes to provide an explanation for loopy cat women, why people don't have any fingerprints, and why a few humans continue to exist nuclear bombs. Genes light up every little thing from JFK's bronze pores and skin (it wasn't a tan) to Einstein's genius. They end up that Neanderthals and people bred hundreds of thousands of years extra lately than any people may suppose cozy considering. they could even let a few humans, due to the unparalleled flexibility in their thumbs and palms, to turn into actually singular violinists.
Kean's shiny storytelling once more makes technological know-how exciting, explaining human historical past and whimsy whereas displaying how DNA will impact our species' future.
Read or Download The Violinist's Thumb: And Other Lost Tales of Love, War, and Genius, as Written by Our Genetic Code PDF
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Additional resources for The Violinist's Thumb: And Other Lost Tales of Love, War, and Genius, as Written by Our Genetic Code
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1998), (Wang, 2000). A number of pathological conditions have been associated with disturbances of the calpain system, among them: cataractogenesis, inflammation, arthritis, Alzheimer’s 29 E. Carafoli and M. ), Calcium Signalling and Disease, 29–53. © 2007 Springer. , 1993) and Parkinson’s diseases (Vanderklish and Bahr, 2000). The list could continue to include organ ischemia, stroke, brain trauma, various platelet syndromes, hypertension, liver dysfunction, and some types of cancer: Table 1 offers a panorama of the diseases that have most frequently been linked to calpains.
Glycation of annexin II as a putative mechanism for impaired fibrinolysis in diabetic patients. Med. Hypotheses 59, 247–251. , and J. Chacko, 1994, An endothelial cell receptor for plasminogen/tissue plasminogen activator. I. Identity with annexin II. J Biol Chem. 269(33):21191–7. , 1993, Homocysteine-induced modulation of tissue plasminogen activator binding to its endothelial cell membrane receptor. J. Clin. Invest 91, 2873–2879. , and S. Krishnan, 1999, Annexin II: a mediator of the plasmin/plasminogen activator system.
All the identified mutations fell inside gene CPN3, encoding calpain-3 (Sorimachi et al 1989). , 1996).