Epigenetics: The Ultimate Mystery of Inheritance by Richard C. Francis

By Richard C. Francis

Time to fret again—our way of life offerings do impression our genetic code and that of our youngsters (and even grandchildren!)."The strength is extraordinary. . . . The age of epigenetics has arrived."—Time, January 2010 Epigenetic capability "on the gene," and the time period refers back to the contemporary discovery that pressure within the setting can influence an individual's body structure so deeply that these organic scars are literally inherited via the subsequent a number of generations. for example, a up to date research has proven that males who began smoking sooner than puberty brought on their sons to have considerably better premiums of weight problems. And weight problems is simply the end of the iceberg—many researchers think that epigenetics holds the main to realizing melanoma, Alzheimer's, schizophrenia, autism, and diabetes. Epigenetics is the 1st booklet for common readers in this attention-grabbing and critical subject. The ebook is pushed by means of tales reminiscent of the Dutch famine of worldwide conflict II, José Canseco and steroids, the breeding of mules and hinnies, Tazmanian devils and contagious melanoma, and extra. 18 illustrations

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Koo, J. S. Park, Y. H. Choi, H. N. Kim,W. K. Chang, K. K. Lee,Y. M. Han, J. Biol. Chem. 2001, 276, 39980±39984. 73 Y. K. Kang, D. B. Koo, J. S. Park, Y. H. Choi, K. K. Lee,Y. M. Han, FEBS Lett. 2001, 499, 55±58 74 M. Tada,Y. Takahama, K. Abe, N. Nakatsuji, T. Tada, Curr Biol. 2001, 11, 1553±1558. 75 Y. K. Kang, D. B. Koo, J. S. Park, Y. H. Choi, A. S. Chung, K. K. Lee, Y. M. Han, Nature Genet. 2001, 28, 173± 177. 76 J. P. Issa, P. M. Vertino, C. D. Boehm, I. F. Newsham, S. B. Baylin, Proc. Natl.

78 D. M. Bornman, S. Mathew, J. Alsruhe, J. G. Herman, E. Gabrielson. Amer. J. Pathol. 2001, 159, 831±835. 79 H. Tohgi, K. Utsugisawa,Y. Nagane, M. Yoshimura, M. Ukitsu,Y. Genda. Neurosci. Lett. 1999, 275(2), 89±92. 80 W. S. Post, P. J. Goldschmidt-Clermont, C. C. Wilhide, A. W. Heldman, M. S. Sussman, P. Ouyang, E. E. Milliken, J. P. Issa. Cardiovasc. Res. 1999, 43, 985±991. 81 V. L. Wilson, R. A. Smith, S. Ma, R. G. Cutler, J. Biol. Chem. 1987, 262, 9948±9951. 82 J. P. Issa, Crit. Rev. Oncol.

1999, 32, 31±43. 83 J. G. Herman, J. R. Graff, S. Myohanen, B. D. Nelkin, S. B. Baylin, Proc. Natl. Acad. Sci. USA 1996, 93, 9821± 9826. 84 B. L. Cattanach, Genet. Res. 1974, 23, 291±306. 85 K. A. Wareham, M. F. Lyon, P. H. Glenister, E. D. Williams, Nature 1987, 327, 725±727. 86 B. R. Migeon, M, Schmidt, J. Axelman, C. R. Cullen, Proc. Natl. Acad. Sci. USA 1986, 83, 2182±2186. 87 R. Holliday, Understanding Ageing, Cambridge University Press, Cambridge 1995. 88 V. L. Wilson, P. A. Jones, Science 1983, 220, 1055±1057.

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