By Robert Boyle, Clelia Pighetti (ed.)
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8 ) . The result is a slight increase in antigen-binding cells followina primary immunization and a secondary immune response of magnitude approximately equivalent to the primary. With yet other thymus-independent antigens such as those of Brucella abortus, the stimulus to multiplication would be stronger than that to differentiation so that some build up of a memory population and increased secondary response is observed (Fig. 7 ) . These hypotheses are testable. For example, it should be possible with the electronic cell sorter to obtain populations of B lymphocytes with surface receptors for levan.
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Lancet. V k 9 3 6 , 1973. 45. L. , Int. Arch. Allergy. 4^:918, 1971. 46. Roelants, G. , Nature New Biol. 239: 63, 1972. ' 47. , Brostoff, J. , Lancet. 2;367, 1969. 48. , Passaleva, A. , Immunology. 1_9:599, 1970. 49. , Am. Y. Acad. Sei. In press. 50. , Tanazic, V. , Int. Arch. Allergy. 45^:138, 1973. 51. Schimpl, A. , J. Exp. Med. ]37j547, 1973. 52. D. , Arthritis and Rheumatism. J_3:369, 1970. 53. , Nature, London. 54. A. , Proc. Soc. Exp. Biol. ]68;784, 1968. 55. , Transplant. Rev. 1:114, 1969.