Discover (April 2016)

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National parks safeguard nature's beauty for our entertainment, yet in addition they comprise a number of the most interesting outdoors technology labs on the planet. during this factor, you'll get an up-close examine key examine initiatives underway at 10 diversified parks round the usa. may well venomous creepy-crawlies carry the keys to powerful, non-addictive painkillers? See why biochemist Glenn King is very happy to paintings with dinner plate-sized tarantulas and lethal scorpions.

Then, see how a doctor's gamble within the nineteenth century prepared the ground for a brand new melanoma remedy. conversing of likelihood, are most sensible poker gamers and different gamblers expert or just fortunate? And one other burning query: Are extraterrestrial beings at the back of a star's loopy gentle styles? You'll locate solutions to those questions and extra contained in the April factor of detect.

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In May of that year, William B. Coley was the man holding that dubious syringe in the apartment of a 35-year-old Italian immigrant and drug addict named Zola. Poor Zola was told he might have only weeks to live due to an egg-size, inoperable tumor obstructing his pharynx, making it impossible for him to swallow food. Zola’s last shot at survival was in the hands of Coley, a 29-year-old bone surgeon who had just completed his training at New York Memorial Hospital. The young surgeon believed he was holding a cure for cancer in that syringe.

Today’s immunotherapy researchers not only will need to borrow the methods once popularized by Coley, but also his implacable personality. But the tide is certainly turning, and persistence is paying off. “I most admire Coley’s tenacity and stubbornness. He kept moving forward with what he thought was an effective means to destroy cancer, despite his colleagues’ lack of support,” says Saha. ” D IMMUNOTHERAPY’S RESURGENCE BioMed Valley’s intriguing C. novyi treatment is still in its early stages of testing and research, and it’s just one of many ascending immunotherapy treatments.

Salmon this big would become a rarity. The Elwha River rushes through the gap where Glines Canyon Dam once stood. Just after this photo was taken in 2014, the final piece of the dam was removed. CLOCKWISE FROM LEFT: STEVE RINGMAN/SEATTLE TIMES; COURTESY OF MARY ANN DELONG; ELAINE THOMPSON/AP/CORBIS 1 carried away the sediment and deposited most of it in the Strait of Juan de Fuca, the body of water that connects Puget Sound to the Pacific Ocean. Chinooks have been seen in the upper watershed for the first time in 100 years.

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