The Double Helix: A Personal Account of the Discovery of the by James D. Watson

By James D. Watson

The vintage own account of Watson and Crick’s groundbreaking discovery of the constitution of DNA, now with an advent through Sylvia Nasar, writer of an attractive Mind.

By selecting the constitution of DNA, the molecule of lifestyles, Francis Crick and James Watson revolutionized biochemistry and gained themselves a Nobel Prize. on the time, Watson was once basically twenty-four, a tender scientist hungry to make his mark. His uncompromisingly sincere account of the heady days in their exciting dash opposed to different world-class researchers to unravel one in every of science’s maximum mysteries offers a dazzlingly transparent photograph of an international of extraordinary scientists with nice presents, very human goals, and sour rivalries.

With humility unspoiled by way of fake modesty, Watson relates his and Crick’s determined efforts to overcome Linus Pauling to the Holy Grail of existence sciences, the identity of the fundamental construction block of lifestyles. by no means has a scientist been so fair in taking pictures in phrases the flavour of his paintings.

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Grinstein, studies. and C. V . Moore. Brit. J . H a e m a t . 5 : 1959. Haemoglobin synthesis in thalassaemia; in vitro 102-120. , and M . Adinolfi. 1 9 6 2 . Observations on the high foetal haemoglobin gene and its interaction with the thalassaemia gene. J . Clin. Path. 1 5 : 3 5 0 - 3 5 6 . Barnabas, J . , and C. J . fy{$ler, 1 9 6 2 . H a e m o g l o b i n - L e p o r e Beaven, G . , W . B . © t a t z e r , B . 1. ( H o l ] a n d i a ) . Nature ( L o n d . ) 1 8 4 : 9 3 1 . Stevens, E . M . Shooter, M .

This observation suggests that the /^-thalassemia gene in the Far East is usually of the nonhemoglobin A-producing variety. This important point needs verification, particularly since the detailed studies required to exclude the presence of small amounts of hemoglobin A have not always been reported. 2 Several other families have been described in which the ^-thalassemia gene was found in association with the gene for a /2-chain hemoglobin variant. , 1961). In all these families the presence or absence of hemoglobin A in doubly affected persons ran true within sib ships.

S o c . H a e m a t . , V i e n n a . Basel: S. K a r g e r , p. 3 0 2 . — , — , and — . 1 9 6 2 . H e m o g l o b i n 'Pylos': Study o f a hemoglobinopathy resembling thalassemia Blood 1 9 : 1 - 2 2 . in the heterozygous, homozygous and double heterozygous state. , C. P i k , and S. S r i n g a m . 1 9 6 5 . Haemoglobinopathies in T h a i l a n d . distribution of elevations of haemoglobin A 2 I I . Incidence and and haemoglobin F ; a survey of 2 7 9 0 people. Brit. J . H a e m a t . 1 1 : 2 2 7 - 2 3 6 .

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