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Extra resources for Nature (Vol. 436, No. 7054, 25 August 2005)
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B, Barbamide, a molluscicide. c, Syringomycin, an antibiotic. Biosynthesis of all three products involves enzymatic chlorination. 1094 ©2005 Nature Publishing Group of the cortex, he argued, to perform the computations needed to extract invariances despite the different inputs that the environment may provide. The present study1, and those that will no doubt follow, will lead to a more profound understanding of this fundamental problem. ■ Robert J. Zatorre is at the Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.
E. Fryxell and J. Linehan, unpublished results) salts are solids and so are not candidates for smart solvents. Our non-ionic liquid is as nonpolar as chloroform, according to measurements using Nile Red as solvatochromic dye (see supplementary information), whereas the liquid under CO2 is as polar as dimethylformamide or propanoic acid. The polarity changes in this switchable solvent system are demonstrated by testing the solubility of decane, a nonpolar compound, in each liquid: it is miscible with the liquid under N2 but not with that under CO2 (Fig.
Zatorre, R. J. J. Acoust. Soc. Am. 84, 566–572 (1988). 6. Patterson, R. , Johnsrude, I. S. & Griffiths, T. D. Neuron 36, 767–776 (2002). 7. Zatorre, R. J. & Belin, P. Cerebral Cortex 11, 946–953 (2001). 8. , Wagner, T. & Scheich, H. Neurosci. Lett. 252, 115–118 (1998). 9. Whitfield, I. in Cerebral Cortex (eds Peters, A. ) 329–351 (Plenum, New York, 1985). such products (Figs 1a–c), and often serves to generate versatile molecular building blocks for synthetic organic chemists. Ideally, these syntheses would use alkanes — unreactive carbon chains — as their starting materials.